Experts have not sufficiently studied either neuroleptic deficiency syndrome or neuroleptic malignant syndrome, but there are several assumptions based on analysis of the physiological effects of antipsychotic drugs. The main hypotheses explaining the causes of the development of luvox malignant syndrome. The occurrence of deviations indopamine metabolism processes. Antipsychotics reduce the sensitivity of dopamine receptors, which leads to increased muscle tone. This causes an increase in temperature and a strong increase in metabolic processes.

The remaining symptoms of NMS are also explained by the specific effect of antipsychotics on serotonin and dopamine receptors. Effect of antipsychotics on skeletal muscles. The drugs, by provoking dopamine blockade in the periphery, increase the frequency of muscle contractions, which leads to the appearance of symptoms of NMS. It is assumed that this effect is associated with the genetic characteristics of the patient.

If measures are not taken in a timely manner, pathological changes may become irreversible. Tricyclic antidepressants - what are they? Read about it here. The following factors increase the likelihood of developing NMS. Neuroleptic deficiency syndrome develops, according to researchers, due to excessively strong blocking of dopamine receptors by antipsychotic drugs in different areas of the nervous system. Factors that increase the likelihood of VAT occurrence. Medicines designed to reduce the effect of antipsychotics and prescribed together with them can increase the severity of VAT symptoms.

Main symptoms of neuroleptic malignant syndrome. Muscle rigidity. The patient’s muscles are very tense, and resistance is felt during passive movement (its severity varies from person to buy luvox online). This symptom appears first, sometimes the body temperature rises at the same time. Increased body temperature. Typically found between 38.5 and 42 degrees. In rare cases, the patient's body temperature is lower than the specified values. Cases were recorded in which the temperature remained within the physiological norm (36.6). Temperatures in the morning are higher than in the evening. Other extrapyramidal disorders.